Occurrence of Ph-like ALL fusions and correlation with 15-gene LDA predictor score. Distribution of childhood and adult Ph-like ALL cases by 15-gene LDA score and specific Ph-like gene rearrangement.^8,24,45  LDA scores ≥0.5 are considered positive for the Ph-like ALL expression signature. The majority of Ph-like cases have LDA scores ≥0.85, particularly those with ABL class, JAK2, and EPOR rearrangements. Some CRLF2-R cases have lower LDA scores in the 0.5 to 0.8 range.