Genetic markers further stratified patients after FLIPI risks have been applied. Four genetic markers were used to generate an aberration count, including deletions of TP53, CDKN2A, and CREBBP, and gain of CD79B. Kaplan-Meier analyses of the prognostic significance of the aberration count in FL patients with (A) low FLIPI risk (score = 0 or 1) and (B) high FLIPI risk (score = 2). Red, green, and blue lines denote patients positive for 0, 1, or at least 2 markers, respectively.