Mutation landscape of AML with RUNX1-RUNX1T1 or CBFB-MYH11. (A) Identified mutations in analyzed patients are shown. Gray boxes indicate the patients whose samples were not analyzed. (B) The frequency of recurrently mutated genes by CBF-AML fusion type is shown. (C) Circos plots illustrate the association of mutated genes in AML with RUNX1-RUNX1T1 or CBFB-MYH11. (D-E) Circos plots illustrate the association of mutated genes in AML with RUNX1-RUNX1T1 and AML with CBFB-MYH11. The width of the arches indicates the percentage of mutations.