Schematic of the vitamin K3-SIAH2–mediated stabilization of DYRK2 leading to decreased survival and self-renewal of CML LSCs via depletion of c-Myc and activation of p53.
Schematic of the vitamin K3-SIAH2–mediated stabilization of DYRK2 leading to decreased survival and self-renewal of CML LSCs via depletion of c-Myc and activation of p53.