Changes in MAP after 4 weeks according to initial Ann Arbor score. (A) Reverse waterfall plots of changes in MAP and (B) box-and-whisker plots of changes in MAP in consecutive patients who provided samples before and after 4 weeks of treatment according to initial Ann Arbor score in patients with (red line) and without (blue line) 6-month NRM. (Left) Ann Arbor 1 patients (MAP < .141 at treatment initiation). (Center) Ann Arbor 2 patients (0.141 ≤ MAP ≤ .290 at treatment initiation). (Right) Ann Arbor 3 patients (MAP > .290).