Recognition of bacterial carbohydrate epitopes in PADs. (A) Spearman’s rank correlation matrix for IgG recognition of pooled sera to all 121 bacterial carbohydrate structures identified by BCSDB analysis on the CFG array. (B-C) Recognition of bacterial glycans by individual sera screened on the NCFGv2. (B) Dendrogrammed reactivity matrix based on the mean RFU values for all 65 glycans identified by BCSDB analysis. (C) Heat map presentation of glycan-specific IgG binding to selected epitopes from S pneumoniae (n = 2), H influenzae (n = 3), N meningitidis (n = 6), E coli (n = 15), H pylori (n = 15), and Salmonella spp (n = 2).