Figure 1.
Cumulative incidence curves of time to CD19+normal B-cell detection and loss of CD19-directed CAR T-cell detection. (A) Cumulative incidence of peripheral blood normal CD19+ B-cell detection at a level ≥0.01% CD19+ normal B cells in blood leukocytes after day 28 post–CD19-CARTx. (B) Cumulative incidence of loss of peripheral blood CD19-directed CAR T-cell detection, defined as ≤10 FlapEF1α per microgram of DNA on 2 consecutive tests, as detected by quantitative PCR after day 28 post–CD19-CARTx. Participants were censored at the last peripheral blood measurement. The shaded area represents the upper and lower limits of the 95% CIs.

Cumulative incidence curves of time to CD19+normal B-cell detection and loss of CD19-directed CAR T-cell detection. (A) Cumulative incidence of peripheral blood normal CD19+ B-cell detection at a level ≥0.01% CD19+ normal B cells in blood leukocytes after day 28 post–CD19-CARTx. (B) Cumulative incidence of loss of peripheral blood CD19-directed CAR T-cell detection, defined as ≤10 FlapEF1α per microgram of DNA on 2 consecutive tests, as detected by quantitative PCR after day 28 post–CD19-CARTx. Participants were censored at the last peripheral blood measurement. The shaded area represents the upper and lower limits of the 95% CIs.

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