PLA2G4A expression in MDS and impact on survival. (A) Relative PLA2G4A gene expression using the National Center for Biotechnology Information GEO data set, GDS3795 showing significantly higher gene expression in MDS case subjects compared with control subjects. (B) Relative PLA2G4A gene expression using the NTUH independent data set confirming significantly higher PLA2G4A gene expression in MDS case subjects compared with control subjects. (C) Higher PLA2G4A gene expression is associated with higher risk disease subtypes in RAEB1, RAEB2, and RAEB-T. (D) Kaplan-Meier plot showing that lower PLA2G4A gene expression is associated with improved overall survival. Error bars represent mean ± standard error. *P < .005, **P < .0001.