Comparison between RS-AML and SF3B1^mutAML and MDS. (A) Heat map of gene expression by supervised k-means clustering in RS-AML, SF3B1^mut AML, and SF3B1^mut MDS vs control NBM cells. The expression of the 6 clusters identified in for individual groups is shown on the right. (B) Biological process enrichment for cluster 5 as identified in panel A; for other clusters, see supplemental Figure 3. (C) Gene overlap of common upregulated genes among RS-AML, SF3B1^mut AML, and SF3B1^mut MDS vs control. Biological process enrichment is shown for commonly upregulated genes.