eRNA activates VEGFR2 in a murine cremaster model of inflammation activation. In a cremaster model of inflammation, adherent leukocytes (A) and the rolling flux fraction (B) were investigated using intravital microscopy in venules of mice pretreated with semaxanib blocking VEGFR2 or solvent (DMSO) and stimulated with TNF-α or RNA. Data are mean ± SEM. n > 10 per group. *P < .05, 1-way ANOVA with the Bonferroni multiple-comparison test.