Anti-CD47 antibody efficacy is macrophage-mediated in TCL PDX. (A) Burden at involved sites for each mouse. P values by 2-sided Welch t test. (B) Flow plots of Gr-1⁺ neutrophils in the peripheral blood of mice before and after treatment with anti-Ly6G Ab. (C) Flow plots of F4/80⁺ macrophages in the peripheral blood of mice before and after treatment with clodronate. PBS, phosphate-buffered saline.