Table 3.

Randomized phase 3 studies of cGVHD initial therapy

Randomized phase 3 studies of cGVHD initial therapy

PDN indicates prednisone; CNI, calcineurin inhibitor; Thal, thalidomide; HCQ, hydroxychloroquine; and NA, not available.

*All randomized patients had platelet count > 100 000/μL.

†All patients had high-risk cGVHD (ie, thrombocytopenia and progressive onset).

‡Multicenter trial (treatment failure was defined as the initiation of secondary therapy or bronchiolitis obliterans or recurrent malignancy or death from causes other than recurrent malignancy).

§COG multicenter trial.

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