The WBC count is higher in CML than either CMML or atypical CML, including WBCs greater than 200 × 10⁹/L. The percentage of monocytes is generally greater than 10% in CMML, higher than in either CML or atypical CML. CML shows a prominent basophilia compared with CMML and atypical CML. Large numbers of immature granulocytes are typical of CML, with fewer numbers in atypical CML and even less in CMML. Greater numbers of circulating blasts are seen in atypical CML than in either CMML or chronic-phase CML. Finally, atypical CML has the most granulocytic dysplasia, which is generally absent in CML and may be present or absent in CMML.

Adapted with permission from Pereira et al,⁷  page 99.