Table 1.

Neonatal hemostasis versus older children/adult hemostasis

Neonatal hemostasis versus older children/adult hemostasis

NA indicates not available; APCR, activated protein C resistance; and TFPI, tissue factor pathway inhibitor.

For reference values of coagulation and regulation of coagulation factors, see Monagle et al, 2006.14 

*Maximum age reported.

†Decreased response was reported to agonists such as thrombin, collagen, epinephrine, and thrombin activation peptide as tested by flow cytometry.

‡Lower levels compared with adults are reported from 1 mo to 16 y of age.

§Higher levels in extremely preterm neonates on d 10 of life compared with older preterm or term neonates.

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