Figure 5
Figure 5. Impairment of Treg-mediated inhibition of IFN-γ production by effector T cells in AA. (A,C) The levels of IFN-γ measured in the supernatants from the proliferation and suppression assays showed that both PB- and BM-derived Tresp and Tcyt from AA patients (n = 6) postcocultured with autologous Tregs had significantly higher levels of IFN-γ production compared with those of controls (n = 6). (B,D) Percentages of inhibition of IFN-γ production were shown. *P < .05; **P < .001.

Impairment of Treg-mediated inhibition of IFN-γ production by effector T cells in AA. (A,C) The levels of IFN-γ measured in the supernatants from the proliferation and suppression assays showed that both PB- and BM-derived Tresp and Tcyt from AA patients (n = 6) postcocultured with autologous Tregs had significantly higher levels of IFN-γ production compared with those of controls (n = 6). (B,D) Percentages of inhibition of IFN-γ production were shown. *P < .05; **P < .001.

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