Figure 1
Figure 1. ADX40-A20 conjugate vaccine batch testing. (A) ADX40-A20 conjugate binds efficiently down to a concentration of 0.5 μg/mL in the CD40/anti–mouse hybrid ELISA, whereas at a concentration of 10 μg/mL, parental A20 and ADX40mAbs do not bind. (B) Binding of ADX40-A20 to CD40-expressing L929 cells is shown as an increase in fluorescence and a shift to the right (white peak) compared with the negative control 20C2-A20 conjugate (gray peak).

ADX40-A20 conjugate vaccine batch testing. (A) ADX40-A20 conjugate binds efficiently down to a concentration of 0.5 μg/mL in the CD40/anti–mouse hybrid ELISA, whereas at a concentration of 10 μg/mL, parental A20 and ADX40mAbs do not bind. (B) Binding of ADX40-A20 to CD40-expressing L929 cells is shown as an increase in fluorescence and a shift to the right (white peak) compared with the negative control 20C2-A20 conjugate (gray peak).

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