Follow-up of the 10 USS patients. The 10 USS patients benefited from a follow-up (7 subsequent pregnancies). Patient 21 died of a cerebral tumor during the follow-up. Two patients relapsed either after the pregnancy (patient 8) or during subsequent pregnancies led without prophylaxis (patient 5 and 8). Seven patients did not relapse, including 4 patients who had another pregnancy under prophylaxis, allowing favorable maternal and baby outcomes.