Mean steady-state serum concentrations of continuously intravenously infused blinatumomab in up to 4 consecutive treatment cycles. Css were calculated for the indicated number of evaluable patients per cycle and the mean Css ± SD is shown for each cycle. Denominators give the total number of treated patients in each cycle. The P value for the nonsignificant difference between cycle 1 and 4 is depicted by a bracket. Likewise, all other cycles did not differ significantly among each other. Css indicates steady-state serum concentration.