Kaplan-Meier curves demonstrating OS from diagnosis based on various risk factors. (A) Comparison of OS between patients with standard-risk MM (n = 370) based on FISH testing with those with high-risk MM (n = 114). (B) Comparison of OS between those with standard-risk MM (n = 370), high-risk MM with any trisomy (n = 48), and high-risk MM without any concurrent trisomy (n = 66). (C) Comparison of OS among patients with any trisomy (n = 275) with or without high-risk FISH features.