Figure 4
![Figure 4. Inhibitory effect of RAP on the interaction of the (β15-66)2 fragment with the VLDLR detected by SPR. (A) RAP (50nM; solid line), 500nM (β15-66)2 (dotted line), or their mixture [50nM RAP + 500nM (β15-66)2] (broken line), were added to immobilized VLDLR and their association/dissociation was monitored in real time. (B) The same mixture of RAP and (β15-66)2 was added after the addition of 50nM RAP (solid line) or 500nM (β15-66)2, (broken line); arrows indicate injection of the mixture. The curves are representative of 2 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/119/2/10.1182_blood-2011-09-382580/5/zh89991184400004.jpeg?Expires=1724233859&Signature=o6aRRH-xdRd53NomhL3oaCYhd1kSrKGjGOoo8Ry8EZUZxlTiHiloj0KYBS0Oh4~79wpIAWokQBGbdlISPBlD1ht0TynAFmq1Uuvx9S9q91~UWp6N5L0EzRym7UqfnKuzC111galzUA5o-8JHCqKg5J8uQX6MjCEJSE7j0qsBCZU2ynvRwT5sc2FJa8TW40Ioo~Rs-GzHjkWFQq7-aC~b6DZHAiU8DK1TwF0cR49oKHHdKE4sLhFhtHGIMxpItiI0aDM2y1ua0RSHyjbO3epBVeeLKCfVhTVHy7PMJMTdB7zSshLFJ2JbefOHzQPx7ei~4iMPIHEFQp662oLPbK2ryg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Inhibitory effect of RAP on the interaction of the (β15-66)2 fragment with the VLDLR detected by SPR. (A) RAP (50nM; solid line), 500nM (β15-66)2 (dotted line), or their mixture [50nM RAP + 500nM (β15-66)2] (broken line), were added to immobilized VLDLR and their association/dissociation was monitored in real time. (B) The same mixture of RAP and (β15-66)2 was added after the addition of 50nM RAP (solid line) or 500nM (β15-66)2, (broken line); arrows indicate injection of the mixture. The curves are representative of 2 independent experiments.
