Variables independently predictive of outcome in NCI HR. After stepwise multivariate analysis, only 2 variables were independently correlated with outcome among the NCI HR cases. Their univariate impacts are shown: (A) MRD and (B) high CRLF2 expression. (C) The performance of the final model of these 2 variables. (D) The model split by its 4 categories to illustrate the relative impact of the variables.