Effects on serum sIL-6r concentrations by LOH in 64 baseline MM patients. (A) Scatter plot of rs2228145 genotype in 626 PBSC (black) and 64 PC (red, green, and blue) samples; the heterozygous group is identified by the shaded oval. The 64 patients used for loss of heterozygosity analysis were identified as heterozygous in germ line samples. Of the 64 PC samples, 38 showed no sign of allele change by scatter plot (green; AC–No change), 14 showed a gain of allele C (red; AC–Amp C), and 12 showed a gain of allele A (blue; AC–Amp A). (B) Serum sIL-6r levels in the 64 patients, segregated by allele change and color-coded to match panel A.