Figure 2
Detection of human neutrophils in NSG mouse blood. (A) Representative FACS plots showing the distinction of human CD45+CD15/66b+ neutrophils in the blood (left panel) and BM (right panel) of a NSG mouse transplanted with human Lin−ALDH+ CB cells. (B) Linear relationship between the dose of Lin−ALDH+ CB cells transplanted and the level of human neutrophils detected 3 weeks later in the BM. Shown are the mean ± SEM of data pooled from 7 experiments (2-5 mice per cell dose per experiment).

Detection of human neutrophils in NSG mouse blood. (A) Representative FACS plots showing the distinction of human CD45+CD15/66b+ neutrophils in the blood (left panel) and BM (right panel) of a NSG mouse transplanted with human LinALDH+ CB cells. (B) Linear relationship between the dose of LinALDH+ CB cells transplanted and the level of human neutrophils detected 3 weeks later in the BM. Shown are the mean ± SEM of data pooled from 7 experiments (2-5 mice per cell dose per experiment).

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