Figure 1
MAF and target genes are highly expressed in myelomas with MAF or MMSET translocations. Expression of MAF and target genes in primary MM patient samples were derived from Affymetrix U133plus2.0 gene expression profiling data from 451 purified bone marrow plasma cell populations collected from untreated patients with MM (A-D) or 47 MM cell lines (E-F). Samples are ranked according to the expression of MAF itself (A,C,E, average of 4 probe sets) or the average expression of MAF and 3 target genes (B,D,F). Expression was centered based on the mean value in normal plasma cells (GEO dataset GSE5900). Myeloma subgroups are designated according to Zhan et al.3

MAF and target genes are highly expressed in myelomas with MAF or MMSET translocations. Expression of MAF and target genes in primary MM patient samples were derived from Affymetrix U133plus2.0 gene expression profiling data from 451 purified bone marrow plasma cell populations collected from untreated patients with MM (A-D) or 47 MM cell lines (E-F). Samples are ranked according to the expression of MAF itself (A,C,E, average of 4 probe sets) or the average expression of MAF and 3 target genes (B,D,F). Expression was centered based on the mean value in normal plasma cells (GEO dataset GSE5900). Myeloma subgroups are designated according to Zhan et al.

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