Figure 4
![Figure 4. FdUMP[10] causes S-phase arrest regardless of p53 status. (A) EdU (5-ethynyl-2′-deoxyuridine) incorporation assays. MLL-ENL–driven murine AML cells were incubated with the indicated drug for 8 hours and subjected to an EdU incorporation assay. S-phase cells were gated as shown. Percentages shown are for cells in S phase. (B) EdU incorporation assay as in panel A. Cells were infected with either a p53-targeting shRNA or a control vector and exposed to the indicated drug for 8 hours.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/119/15/10.1182_blood-2011-06-362442/5/zh89991288960004.jpeg?Expires=1722430905&Signature=PQtJVIKO3jkHTo4BYlwPp88AmVGhXWmpg4eQlnvBpaRalB6mVmM2JpX4SqJPhULENwtp4kuKJp9~TYWpE23s~J0craQZFNK-ggTaK9Vp61EchhbjPl8dJauapmZHj52BaMLM2~~zhKt6tRWbjvvoAK7LYgPvrnCjSGk7hZr91KxLAW8pKmeyHQfFA9MYPT9uqitmx2fkXtlx359X8nRPUulCw8koV4krDyIsO1jOu8CIy4MqVAbqpK8Qix04G4iwcq3wHtwoPH4Hs-9qs1QnXHffPHST336z-4vYo11m84CEgitFnXccWFdgEhWaqxFPDq3TTREBVDc0vWGgsMR8Yg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
FdUMP[10] causes S-phase arrest regardless of p53 status. (A) EdU (5-ethynyl-2′-deoxyuridine) incorporation assays. MLL-ENL–driven murine AML cells were incubated with the indicated drug for 8 hours and subjected to an EdU incorporation assay. S-phase cells were gated as shown. Percentages shown are for cells in S phase. (B) EdU incorporation assay as in panel A. Cells were infected with either a p53-targeting shRNA or a control vector and exposed to the indicated drug for 8 hours.
