Figure 6
Effects of TIMP-3 on HSCs and MPPs. TIMP-3 stimulates cell-cycle progression of HSCs and thus promotes production of MPPs. TIMP-3 does not affect proliferation of MPPs. In addition, TIMP-3 acts to preserve multilineage differentiation potential of HSC progenies.

Effects of TIMP-3 on HSCs and MPPs. TIMP-3 stimulates cell-cycle progression of HSCs and thus promotes production of MPPs. TIMP-3 does not affect proliferation of MPPs. In addition, TIMP-3 acts to preserve multilineage differentiation potential of HSC progenies.

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