IgG titers are elevated in IL-17RA^KO mice. (A) Sera from mice described in Figure 1 were analyzed for Pg-specific IgG in WT (□) and IL-17RA^KO (▪) mice by ELISA.⁴¹  Standard deviations are shown. *Statistically significant differences in Pg-infected samples compared with sham-infected samples of the same strain, as determined by unpaired t test (P < .05). There was no significant difference between WT Pg-infected IgG and IL-17RA^KO sham-infected IgG levels. (B) Total IgG levels in uninfected WT (□) and IL-17RA^KO (▪) mice were determined in triplicate by ELISA. Standard deviations are shown. *Statistically significant difference compared with WT determined by unpaired t test (P < .05).