Table 2.
A comparison of two classes of anticoagulant used to treat HIT
Check mark (
) indicates favorable feature in comparison of drug classes. Reprinted, with modifications and permission, from Warkentin 2010.30
ACS indicates acute coronary syndrome; INR, International Normalized Ratio.
*For danaparoid, half-lives of its anti-thrombin and its thrombin generation inhibition activities (2-4 h and 3-7 h, respectively) are shorter than for its anti-Xa activity (∼ 25 h).
†Although therapeutic dosing is recommended for HIT, availability of prophylactic-dose regimens increases flexibility when managing potential non-HIT situations.
