Table 2.

Key genetic and immunophenotypic features in DLBCL: GCB, ABC, and primary mediastinal DLBCL (PMBL)

Key genetic and immunophenotypic features in DLBCL: GCB, ABC, and primary mediastinal DLBCL (PMBL)

m indicates mutation; amp, amplification.

*MUM1/IRF4 is expressed in GCB-DLBCLs that have IRF4 translocations

†BCL2 expression is ABC-DLBCL is not always dependent on genetic amplification (it may reflect cell of origin). BCL2 is expressed in GCB-DLBCLs that harbor the t(14;18) translocation.

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