American Society of Hematology

Figure 1.

$Figure 1. Relationship between clinical HIT and antibody formation. Only a minority of patients with heparin-PF4 antibodies shown by ELISA demonstrate functional antibodies by SRA, and only a fraction of these will develop clinical disease (HIT or HIT-T). The true frequency of antibody formation and an accurate estimate of risk for clinical disease in the pediatric population are not well known.$

Relationship between clinical HIT and antibody formation. Only a minority of patients with heparin-PF4 antibodies shown by ELISA demonstrate functional antibodies by SRA, and only a fraction of these will develop clinical disease (HIT or HIT-T). The true frequency of antibody formation and an accurate estimate of risk for clinical disease in the pediatric population are not well known.

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