nCR indicates near CR; V, bortezomib (Velcade); T, thalidomide; D, dexamethasone; B, bortezomib; PLD, pegylated liposomal doxorubicin; iv, intravenous; Mel, melphalan; Dex, dexamethasone; M, melphalan; P, prednisone; Cy, cylophophosphamide.