Figure 5
Increased mIL-6 expression in PLNs and spleen of vIL-6tg2 mice. IHC for mIL-6 in lymph node (PLN; A-B) and spleen (C-D) from 21-week-old wild-type (A,C; 20-fold magnification) and vIL-6tg2 (B,D; 40-fold magnification) mice. A subset of sinusoidal cells in PLN tissue expressed mIL-6 only in transgenic mice (B). A subset of cells in the red pulp of spleens from transgenic mice expressed mIL-6 (D).
