Figure 4
Figure 4. Peptide+/human leukocyte Ag+ CD8+ T cells and B-cell receptor–ABL levels. (A) FACS heat map of KQSSKALQR/human leukocyte Ag-A3 pentamer+ CD8+ T cells detectable in the peripheral blood of patient 9 at 3 weeks after the third infusion of the in vitro-generated CTL preparation. As demonstrated in panel B, this was accompanied by the detection of 1.5% ATGFKQSSK/human leukocyte Ag-A11/-A3 pentamer+ CD8+ T cells. The patient has remained in molecular remission throughout follow-up, with no signs of acute or chronic GVHD (C).

Peptide+/human leukocyte Ag+ CD8+ T cells and B-cell receptor–ABL levels. (A) FACS heat map of KQSSKALQR/human leukocyte Ag-A3 pentamer+ CD8+ T cells detectable in the peripheral blood of patient 9 at 3 weeks after the third infusion of the in vitro-generated CTL preparation. As demonstrated in panel B, this was accompanied by the detection of 1.5% ATGFKQSSK/human leukocyte Ag-A11/-A3 pentamer+ CD8+ T cells. The patient has remained in molecular remission throughout follow-up, with no signs of acute or chronic GVHD (C).

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