Bone marrow mobilization of mature PMNs into the peripheral blood circulation in response to S aureus wound infection. Mature EGFP-PMNs were gated on EGFP^highGr-1^high cells. Shown are the kinetics of EGFP^highGr-1^high cells in the bone marrow (A) and peripheral blood (B) from mice treated with either sterile saline or S aureus (1 × 10⁷ CFUs). Data are derived from 3-4 mice in each group and are expressed as means ± SEM. *P < .05 vs the saline group; **P < .01 vs the saline group.