Figure 5
![Figure 5. Host LCs are not required for priming graft-versus-host reactivity in the steady state. DT or PBS was given intraperitoneally to [B6 + BALB/c] → Langerin.DTR MCs on day −2 and day 4 after splenocyte transfer. (A) Absolute numbers of Thy1.1+ CD4 and CD8 cells in recipient spleen and LN on day 14 in MCs treated with or without DT (n = 7 mice per group); data pooled from 4 independent experiments. The mean is indicated by the horizontal bar. (B) Specific cytotoxicity in vivo directed against B6 strain B cells on day 14 (n = 5 or 6 mice per group); data pooled from 3 independent experiments. The mean is indicated by the horizontal bar.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/117/26/10.1182_blood-2011-01-329185/5/zh89991173940005.jpeg?Expires=1724944391&Signature=C8zxEGh~xyDzcnf-zpbTfUCVsudfHYSpXaboLc3ffRlO5AGITMraD6bMjvBTmHGTe6uKSCqC9N7efLE5NFMSDwzoscndZ4EvddX~tEDz1zzlG-OigBDhY6wgmbJxBKnqfWCR3k~YFJytBDPIZdhhdgL5vOhCGcb8pDYPzupg1laNh1SuyNmM7dzWdm1uIwB2umoZ7FzDWCGZ~wIoFuMLnxjtMjSyzeVE5iHS8urA3kqd-MeaLp86xTt5OwFSezPL1Zah~LbtK36974ETaMXaO0jFsK80fhCAACISQCZdshw49ezaE7VVwTRGc9-v6OFlQ-UjRPzphow8Vbr8FvrbHQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Host LCs are not required for priming graft-versus-host reactivity in the steady state. DT or PBS was given intraperitoneally to [B6 + BALB/c] → Langerin.DTR MCs on day −2 and day 4 after splenocyte transfer. (A) Absolute numbers of Thy1.1+ CD4 and CD8 cells in recipient spleen and LN on day 14 in MCs treated with or without DT (n = 7 mice per group); data pooled from 4 independent experiments. The mean is indicated by the horizontal bar. (B) Specific cytotoxicity in vivo directed against B6 strain B cells on day 14 (n = 5 or 6 mice per group); data pooled from 3 independent experiments. The mean is indicated by the horizontal bar.
