Best radiographic responses. (A) Percentage change in sum of the products of 6 representational lymph nodes at time of best radiographic response compared with baseline, in the 11 patients with pathologic lymphadenopathy at baseline evaluable. Patients can have a radiographic complete response with < 100% decrease in sum of the products of representational lymph nodes as long as there is no pathologic adenopathy at time of evaluation. (B) Percentage change in longest dimension of spleen size (normalized to spleen upper limit of normal = 12 cm) at time of best radiographic response compared with baseline, 10 patients with splenomegaly at baseline evaluable, maximum normalization = 100%.