Quantitative kinetics of T-cell subset reconstitution after Ab-mediated CD4⁺ or CD8⁺ lymphocyte depletion. The data on the reconstitution of total CD4⁺ (A) or CD8⁺ (B) T-cell pools, as well as their naive, memory, and effector subsets in individual SMs and RMs, were fitted to a bilinear model. In this model, an initial rapid phase (phase 1 left graphs) and a second slower phase (phase 2 right graphs) of increase of cell numbers was distinguished. The levels of T-cell reconstitution are graphed as cells/μL blood/day for each of the 3 uninfected SMs and 3 uninfected RMs included in the study, with bars representing the 95% confidence interval of the estimated parameter.