TEG parameters in the placebo or 80-μg/kg groups in experiment 2. TEG parameters in subject treated with placebo or 80 μg/kg rFVIIa at (A) time to clot onset, R, (B) time to achieve 20-mm clot strength, K, (C) angle, (D) maximum amplitude, MA, and (E) time to maximum amplitude, TMA. B0 indicates biopsy 0 (before warfarin treatment); B1, biopsy 1 (after warfarin treatment to achieve an INR of 2.5 ± 0.3); B2, biopsy 2 (15 minutes after rFVIIa or placebo treatment); B3, 5 hours after B2. Arrow indicates time of rFVIIa administration.