Figure 7
Figure 7. Proposed model for biologic consequences of miR-144 overexpression in SCD. We propose that miR-144 is a genetic modifier of oxidative stress tolerance in HbSS erythrocytes and can contribute to the varying clinical severity of SCD.

Proposed model for biologic consequences of miR-144 overexpression in SCD. We propose that miR-144 is a genetic modifier of oxidative stress tolerance in HbSS erythrocytes and can contribute to the varying clinical severity of SCD.

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