Figure 5
Treatment with anti-CSF1R prevented the recruitment of EGFP+ cells into tumor mass. MacGreen mice were inoculated subcutaneously with 1 × 106 mesothelioma cells and tumor nodules allowed to develop until just palpable, at which point treatment with anti-CSF1R or isotype antibody was commenced. (A) csf1r-EGFP and F4/80 expression in tumor (magnification, ×20) and (B) laser scanning quantitation of csf1r-EGFP expression and F4/80 staining within tumor. (C) Analysis of tumor growth.
