GATA3 has no antiapoptotic or prosurvival effect in HL. (A) MTT assay on transduced L-1236 cells 2, 3, 5, and 7 days postinfection (dpi). Results for mock infected cells were set as 100% viable cells. Values presented are the mean of triplicate measurements. (B) Protein lysates of L-1236 cells after viral small hairpin RNA transfer were assayed for GATA3, cleaved caspase-3, and actin abundance 5 days after infection. Treatment with doxorubicin for 48 hours served as a positive control for apoptosis induction. One representative assay of 3 independent experiments is given.