Normal Tln1^−/− B-cell proliferation in the BM and spleen. BM cells (A) or splenocytes (B) from BrdU-treated WT or CD19 Tln1^−/− mice were stained with anti-BrdU antibodies, and for either B220 or CD3, as indicated. Data on left are histograms depicting the percentage of BrdU-incorporated cells from those that stained positively for either B220 or CD3; each histogram shows 1 experiment representative of 6. Data on right are the mean ± SD of the BrdU-incorporated cells, which stained for B220 (B cells) or CD3 (T cells). n = 6. N.S. indicates not significant.