Figure 6
Figure 6. Generation of human CD41+ cells in NOD/SCID mice 12 weeks after transplantation with human cord blood cells cultured in the presence of HOXB4 and DL. Mice transplanted with cells cultured in the presence of DL show increased expression of CD41 megakaryocyte marker. (A) Data from 5 replications is represented as mean ± SD. Each bar represents the mean percent human CD41+ of the 5 mice within that group. *P < .05 (B) Flow cytometric data from 1 representative experiment is shown.

Generation of human CD41+ cells in NOD/SCID mice 12 weeks after transplantation with human cord blood cells cultured in the presence of HOXB4 and DL. Mice transplanted with cells cultured in the presence of DL show increased expression of CD41 megakaryocyte marker. (A) Data from 5 replications is represented as mean ± SD. Each bar represents the mean percent human CD41+ of the 5 mice within that group. *P < .05 (B) Flow cytometric data from 1 representative experiment is shown.

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