Figure 3
Figure 3. Nanoliposomal-C6 ceramide delivery resulted in the preferential accumulation of C6 in the mitochondria in leukemic NK cells. Confocal microscopic image of 25μM nanoliposomal-NBD-C6 delivery to RNK16, a rat NK LGL leukemia cell line, showing that NBD-C6 (green) colocalized with cellular mitochondria (red); Cellular nucleus was stained with 4′,6-diamidino-2-phenylindole (blue). Magnification, 63×.

Nanoliposomal-C6 ceramide delivery resulted in the preferential accumulation of C6 in the mitochondria in leukemic NK cells. Confocal microscopic image of 25μM nanoliposomal-NBD-C6 delivery to RNK16, a rat NK LGL leukemia cell line, showing that NBD-C6 (green) colocalized with cellular mitochondria (red); Cellular nucleus was stained with 4′,6-diamidino-2-phenylindole (blue). Magnification, 63×.

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