Figure 1
![Figure 1. Biodistributions of [213Bi]DOTA-biotin in tumor, blood, and normal organs after PRIT with 1F5-SA or CC49-SA FPs. Athymic mice bearing Ramos xenografts were injected with 2.8nM each unlabeled FP followed 20 hours later by 5.8nM CA, and 4 hours after that by 1.2nM [213Bi]DOTA-biotin. Groups of 5 mice were euthanized 10, 45, 90, and 180 minutes after the injection of [213Bi]DOTA-biotin. The radioactivity in the tissues were quantified by gamma counting, corrected for decay, and expressed as the % ID/g of tissue.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/116/20/10.1182_blood-2010-05-282327/7/zh89991060470001.jpeg?Expires=1724241205&Signature=bSk~CST4nmScHFf45q2VD7bC1zmSGlsOi5SL-5DDS29GzLPrPtJazT-Drdc~ByR6PMjJegXOnFwMK-Jr7AlksFykKpMGO75Lrsh8jhCLRDhLcTlkdPtTQL2wVX-Ml~1b1mN8RRvPYQmUDOSmACtHEBEpIHrbY6jw8tWO9Xxx0Sl7QjJYvGS2z3pAhEDM4~AuapqrYwJfKl8QQUUwooUOCY6VRrCEIe5I5XzSR965d2Yv6CooIUAtrcXmz-madiOXOto1dXSBEUiRISGVfxohv~oKczRAsWGxs-XQZapPc3DZPotjtRp9zJ6QBAgWYV90Zwd43TVMcEj20n4kHJEHaw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Biodistributions of [213Bi]DOTA-biotin in tumor, blood, and normal organs after PRIT with 1F5-SA or CC49-SA FPs. Athymic mice bearing Ramos xenografts were injected with 2.8nM each unlabeled FP followed 20 hours later by 5.8nM CA, and 4 hours after that by 1.2nM [213Bi]DOTA-biotin. Groups of 5 mice were euthanized 10, 45, 90, and 180 minutes after the injection of [213Bi]DOTA-biotin. The radioactivity in the tissues were quantified by gamma counting, corrected for decay, and expressed as the % ID/g of tissue.
