Morphology and cytogenetic analysis of a bone marrow sample of t(X;17)(p11;q12) APL. Leukemic promyelocytes before treatment. (A-B) May-Giemsa staining. (C) Sudan black B staining. (D) Myeloperoxidase staining. Original magnification ×400 for all panels. The black, blue, and red arrows show rectangular cytoplasmic bodies, round inclusions, and Auer-like bodies, respectively. (E) Karyotype analysis. 45,−Y,t(X;17)(p11;q12) was detected in 95% of the cells. (F) FISH analysis. One of the RARA signals is split as (s). Other intact signals of RARA and PML are shown as (r) and (p), respectively.