Preserved numbers of multilineage, myelo-erythroid, and common lymphoid progenitors after Men1 inactivation. Flow cytometric analysis of progenitor populations in the BM of control CreER^Tm+Men1^+/+ mice and menin-deficient CreER^Tm+Men1^f/f mice. The analysis was performed at least 3 weeks after TAM administration. (A) Representative examples, with progenitor populations identified as follows: LSK progenitors (containing hematopoietic stem cells); CLP, common lymphoid progenitors (Lin⁻IL-7Rα⁺AA4.1⁺Flt3⁺); CMP, common myeloid progenitors (Lin⁻Sca-1^–c-kit^hiCD34⁺CD16/32^lo); MEP: megacaryocyte-erythroid progenitors (Lin⁻Sca-1^–c-kit^hiCD34⁻CD16/32^lo); GMP, granulocyte-macrophage progenitors (Lin⁻Sca-1–c-kit^hiCD34^hiCD16/32^hi). (B) Absolute cell numbers in calculated in 2 hind legs. ▵: control CreER^Tm+Men1^+/+; ▴: CreER^Tm+Men1^f/f mice. P values indicate the results of a Student t test.