Figure 6
Figure 6. Competitive BM reconstitution reveals cell-intrinsic role for gp96 in B and T lymphopoiesis, but not myelopoiesis. (A) Diagram of experimental design. (B,D,F) Surface staining of the indicated lineages on gated KO (45.2) and WT (45.1/45.2) BM cells from 1:1 BM chimeras 2 weeks and 2 months PTD. (C,E,G) Percentage of KO and WT contribution to total BM myeloid cells (C), BM B-cell subsets (E), and thymocytes (G) at 2 weeks and 2 months PTD (DN: CD4−CD8−; double-positive: CD4+CD8+; 4: CD4+CD8−; 8: CD4−CD8+). Data are representative of 3 mice per group. *P < .05.

Competitive BM reconstitution reveals cell-intrinsic role for gp96 in B and T lymphopoiesis, but not myelopoiesis. (A) Diagram of experimental design. (B,D,F) Surface staining of the indicated lineages on gated KO (45.2) and WT (45.1/45.2) BM cells from 1:1 BM chimeras 2 weeks and 2 months PTD. (C,E,G) Percentage of KO and WT contribution to total BM myeloid cells (C), BM B-cell subsets (E), and thymocytes (G) at 2 weeks and 2 months PTD (DN: CD4CD8; double-positive: CD4+CD8+; 4: CD4+CD8; 8: CD4CD8+). Data are representative of 3 mice per group. *P < .05.

Close Modal

or Create an Account

Close Modal
Close Modal