Figure 4
Figure 4. Recovery in c-MybPlt4/+ and p300Plt6/+ mice after bone marrow transplantation. Platelet count (top panel), white blood cell count (middle panel), and hematocrit (bottom panel) in (A) c-MybPlt4/+ (squares) or wild-type (c-Myb+/+, circles) mice, and (B) p300Plt6/+ (triangles) or wild-type (p300+/+, circles) mice were determined after whole body irradiation (11 Gy) and intravenous transfusion of 2 × 105 isogenic bone marrow cells. Data points represent the mean ± SD from separate cohorts of mice analyzed at the times indicated. *P < .05 in Student t test for comparison of data from c-MybPlt4/+ mice with that of c-Myb+/+ controls, or p300Plt6/+ mice with that of p300+/+ controls. n = 2 (closed symbols) or 3 to 8 mice (open symbols) per point.

Recovery in c-MybPlt4/+ and p300Plt6/+ mice after bone marrow transplantation. Platelet count (top panel), white blood cell count (middle panel), and hematocrit (bottom panel) in (A) c-MybPlt4/+ (squares) or wild-type (c-Myb+/+, circles) mice, and (B) p300Plt6/+ (triangles) or wild-type (p300+/+, circles) mice were determined after whole body irradiation (11 Gy) and intravenous transfusion of 2 × 105 isogenic bone marrow cells. Data points represent the mean ± SD from separate cohorts of mice analyzed at the times indicated. *P < .05 in Student t test for comparison of data from c-MybPlt4/+ mice with that of c-Myb+/+ controls, or p300Plt6/+ mice with that of p300+/+ controls. n = 2 (closed symbols) or 3 to 8 mice (open symbols) per point.

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