Recipient MBL levels (mannan binding) during the peritransplantation period. Recipient MBL mannan-binding (A) and C4-deposition (B) levels are shown stratified by recipient MBL2 coding genotype and the use of myeloablative total body irradiation in the conditioning regimen. There is a significant increase in MBL levels most evident in recipients lacking MBL2 coding mutations who received mTBI. The increase is maximal from baseline (prior to commencement of conditioning) to the 14th day after transplantation. Bars show mean plus SEM.